Down Syndrome B-Lymphocyte Subpopulations, Intrinsic Defect or Decreased T-Lymphocyte Help

ALTERATION OF T-LYMPHOCYTE SUBPOPULATIONS IN SUBACUTE AND CHRONIC BRUCELLOSIS

Human brucellosis is a major health problem in developing countries. A number of patients with human brucellosis do not recover from the acute stage of the disease and pass into the chronic form. Since the pathophysiology of this change is not well understood, we studied the T-cell subsets during the acute, subacute and chronic forms of human brucellosis. In this study we found alterations...

T-lymphocyte subpopulations in uveitis.

Following an inconclusive study of differential lymphocyte counts in uveitis in which the peripheral blood was examined only once in the course of each case a longitudinal study has been carried out in patients with acute anterior uveitis. Venous blood lymphocytes were examined at intervals throughout the course of the illness, from presentation until six months later. No changes in E-rosetting...

Lymphocyte subpopulations.

B lymphocyte subpopulations in chronic lymphocytic leukemia.

We have defined two subpopulations of B lymphocytes in chronic lymphocytic leukemia (CLL). The major variant (termed typical) was characterized by the presence of a relatively homogeneous population of small-to-medium-sized lymphocytes with low-density SmIgM and no evidence of intracellular Ig synthesis. A minor group (termed atypical) was identified by the presence of a pleomorphic cell popula...

T-Lymphocyte subpopulations in hemophiliac patients.

Laboratory data are presented on 15 patients with hemophilia A. Mean OKT4/OKT8 ratio in hemophiliac patients was significantly lower than in the controls. Although no patients with acquired immunodeficiency syndrome (AIDS) have been found in Japan, hemophiliac patients are supposed to be at increased risk of AIDS by our studies.